Posted on March 22, 2010.
How to treat Gardnerella vaginalis
In women, the main symptom of a lesion is not specific (bacterial) vaginitis. Due to the fact that in vaginal secretions are low in white blood cells, and is dominated by epithelial cells, that little inflammatory reaction, a number of foreign authors use the term "vaginosis" to refer to vaginal lesions caused by G. vaginalis. For cell microscopic image of vaginal flora is characterized by abundant kokkobatsillyarnoy covering part of the epithelial cells so they appear to be grainy and the edges of their completely obscured G. vaginalis mass. These "hard core" cells are the mainstay for the vagina gardnerelleza microscopic diagnosis. Incidentally, with Gardnerella always detect different types of anaerobic bacteria, mainly Bacteroides, which replaces the laktobatsillyarnuyu normal flora. Anaerobes are an important part of the flora in women with bacterial vaginosis, while percentage of their good health less than 1% of the total flora of the vagina.
Gardnerella actively damage the epithelial cells, and their polinuklearami fagnotsitoz is incomplete, leading to autolyze host cells. The relationship between Gardnerella and anaerobes is as follows: anaerobic waste products increase the pH of vaginal secretions to a level conducive to an abundant breeding Gardnerella vaginalis, which in turn provide the necessary amino acids anaerobic and destroying epithelial cells. Bacterial vaginitis clinically expressed moderate, less abundant or rare, sticky secretions homogeneous white or gray, with an unpleasant odor, also covering the walls of the vagina. Few foamy discharge. The reaction of acid secretion. When you add in the secret of the alkaline solution, generally there is the smell of rotting fish - the smell of amines cadaverine and others who are apparently products of vital activity of bacteria anaerobes.
Patients complain of the presence of pain, and sometimes harassment itching or burning. In most cases the infection is asymptomatic Gardnerella vaginalis. When vaginitis pathogens are often not only in the vagina, but also in the urethra, the canal of the cervix, which causes symptoms of urethritis and cervicitis slow current. Approximately 1.3 to 1.2 infections gardnerelleznoy accompanied by other urogenital infections: gonorrhea, chlamydia, ureaplasmosis, trichomoniasis and other treatments recommended metronidazole (Flagyl) in 0.5, 2 times daily for 7 days. Less effective and ampicillin amoxicillin , tetracycline active drugs is less than many gardnerella Shammah stable. Can also tinidazole. The men - women sexual partners of bacterial vaginosis Gardnerella often. They reveal not only people with symptoms of urethritis, but also in men, apparently in good health.
gardnerelleznogo clinical urethritis usually occurs malosimptomno and has a tendency to spontaneous clinical recovery. However, during these urethritis sometimes there are complications in the form of prostatitis, kuperita, epididymitis. Until such complications related to the misuse of infection or concomitant gardnerelleznoy infectious agents. Misunderstood the role of anaerobic bacteria: in some patients the urethra bacteroids isolated peptosstreptokokki, peptokokki and others, but their role in the pathology of urethritis in men was not disclosed.
Bacterial Pathogenesis u.